{"id":13,"date":"2017-07-07T20:21:07","date_gmt":"2017-07-07T20:21:07","guid":{"rendered":"http:\/\/utsaengineer.wpengine.com\/faculty-page-example\/?page_id=13"},"modified":"2025-07-12T16:41:08","modified_gmt":"2025-07-12T21:41:08","slug":"research","status":"publish","type":"page","link":"https:\/\/ceid.utsa.edu\/jyye\/research\/","title":{"rendered":"Research"},"content":{"rendered":"<p>[su_heading size=&#8221;16&#8243; align=&#8221;left&#8221;]<span style=\"color: #ff6600;font-size: 24pt\"><strong>Research Projects<\/strong><\/span>[\/su_heading]<\/p>\n<p>Our research is focused on the development of novel biophotonics technologies technologies to tackle critical challenges in biomedical engineering and clinical translation.<\/p>\n<p style=\"text-align: center\"><span style=\"font-size: 18pt;color: #000080\"><strong>Laser Intravascular Lithotripsy for Coronary Artery Calcification<\/strong><\/span><\/p>\n<p>Coronary artery calcification significantly limits the effectiveness of percutaneous coronary interventions by reducing vessel compliance, hindering device delivery, and increasing the risk of restenosis and other adverse clinical outcomes. In collaboration with Dr. Marc Feldman, an internationally recognized interventional cardiologist, our lab is developing a novel laser-based intravascular lithotripsy (IVL) technique to more effectively treat calcified lesions. Promising results have been obtained. The new findings will be published soon.<\/p>\n<p style=\"text-align: center\"><span style=\"font-size: 18pt;color: #000080\"><strong>Optical Biosensing<\/strong><\/span><\/p>\n<p>We have developed and patented a suite of innovative biosensing technologies for both <em>in vivo<\/em> and <em>in vitro<\/em> applications.<\/p>\n<ul>\n<li><strong>Development of a Unique Photonic Crystal Label-free Biosensor <\/strong><\/li>\n<\/ul>\n<p>We have developed and patented a novel label-free biosensor based on a Photonic Crystal used in a Total Internal Reflection (PC-TIR) configuration. The PC-TIR biosensor features an open optical microcavity that facilitates direct molecular access to the sensing surface, enabling highly sensitive and real-time label-free detection. This unique sensor has been evaluated and validated through a wide range of applications, including drug toxicity screening, detection of cardiac biomarkers, differentiation of prostate cancer cells, and quantification of endotoxins.<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-318 size-large\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Liver-on-a-chip-1024x576.jpg\" alt=\"\" width=\"525\" height=\"295\" srcset=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Liver-on-a-chip-1024x576.jpg 1024w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Liver-on-a-chip-300x169.jpg 300w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Liver-on-a-chip-768x432.jpg 768w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Liver-on-a-chip.jpg 1280w\" sizes=\"(max-width: 525px) 100vw, 525px\" \/><\/p>\n<p>A PC-TIR biosensor integrated with a 3D liver-on-a-chip platform for real-time, continuous, and multiplexed monitoring of liver-secreted biomarkers for drug toxicity screening.<strong>\u00a0<\/strong><\/p>\n<ul>\n<li><strong>Development of a Unique Double-Clad Fiber-Optic Probe<\/strong><\/li>\n<\/ul>\n<p>We have developed and patented a double-clad fiber-optic probe for enhanced <em>in vivo<\/em> two-photon fluorescence detection. The double-clad fiber probe significantly improves fluorescence signal collection efficiency from deep tissue, enabling real-time monitoring of biological processes. For example, it has been utilized for monitoring a multifunctional nanoparticle-based drug delivery system in a live mouse model.<\/p>\n<p><img decoding=\"async\" class=\"alignnone wp-image-317 size-large\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Fiber-Probe-1024x576.jpg\" alt=\"\" width=\"525\" height=\"295\" srcset=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Fiber-Probe-1024x576.jpg 1024w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Fiber-Probe-300x169.jpg 300w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Fiber-Probe-768x432.jpg 768w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Fiber-Probe.jpg 1280w\" sizes=\"(max-width: 525px) 100vw, 525px\" \/><\/p>\n<p><span style=\"font-size: 18pt;color: #000080\"><strong>Investigate laser-induced cavitation microbubbles and shockwaves<\/strong><\/span><\/p>\n<p>We investigated laser-induced cavitation microbubbles across various media, including water, tissue phantoms, and cells. Using ultrafast laser pulses and ultrasonic monitoring, we showed that bubble size, lifetime, and collapse dynamics can be independently tuned by controlling laser pulse fluence, total number of pulses delivered, and the period between pulses. We also discovered a novel phenomenon that laser-induced cavitation bubbles can be trapped in a self-focused femtosecond laser beam. Additionally, we developed a multimodal platform integrating optical, acoustic, and electrophysiological techniques for real-time imaging and measurement of single-bubble cavitation and cell membrane disruption. Currently, we focus on utilizing shockwaves generated from the cavitation bubbles for important cardiovascular applications.<\/p>\n<p><img decoding=\"async\" class=\"alignnone wp-image-319 size-large\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Bubble-trapping-1024x576.jpg\" alt=\"\" width=\"525\" height=\"295\" srcset=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Bubble-trapping-1024x576.jpg 1024w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Bubble-trapping-300x169.jpg 300w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Bubble-trapping-768x432.jpg 768w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Bubble-trapping.jpg 1280w\" sizes=\"(max-width: 525px) 100vw, 525px\" \/>.<\/p>\n<p style=\"text-align: center\"><span style=\"font-size: 18pt;color: #000080\"><strong>Photoacoustic Imaging<\/strong><\/span><\/p>\n<p>We developed and patented a cutting-edge optoacoustic sensor featuring an open optical microcavity for highly sensitive detection of high-frequency photoacoustic signals. Complementing this, we also created a patented filtered back-projection algorithm that incorporates a rigorously derived weighting function from the photoacoustic wave equation. This innovation enhances image contrast and resolution, pushing the boundaries of photoacoustic tomography for biomedical applications.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-321 size-large\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/PAT-of-GNR-1024x576.jpg\" alt=\"\" width=\"525\" height=\"295\" srcset=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/PAT-of-GNR-1024x576.jpg 1024w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/PAT-of-GNR-300x169.jpg 300w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/PAT-of-GNR-768x432.jpg 768w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/PAT-of-GNR.jpg 1280w\" sizes=\"(max-width: 525px) 100vw, 525px\" \/><\/p>\n<p style=\"text-align: center\"><span style=\"font-size: 18pt;color: #000080\"><strong>Targeted Drug Delivery<\/strong><\/span><\/p>\n<p>Personalized medicine provides a unique opportunity for patients to receive individually tailored, targeted therapy for optimized treatment efficacy. The ability to control the release of therapeutics in targeted tissues, with a desired spatial distribution, and at an adjustable rate according to the drug response of each individual is important for personalized medicine. We have been working synthesizing a unique hybrid material as a nano-carrier for targeted drug delivery for enhanced cancer treatments.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-322 size-large\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Drug-delivery-1024x576.jpg\" alt=\"\" width=\"525\" height=\"295\" srcset=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Drug-delivery-1024x576.jpg 1024w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Drug-delivery-300x169.jpg 300w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Drug-delivery-768x432.jpg 768w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2025\/06\/Drug-delivery.jpg 1280w\" sizes=\"(max-width: 525px) 100vw, 525px\" \/><\/p>\n<p style=\"text-align: center\"><span style=\"font-size: 18pt;color: #000080\"><strong>Optical Biosensor for Endotoxin Detection<\/strong><\/span><\/p>\n<p>Limulus amoebocyte lysate (LAL) testing has been an important part of the pharmaceutical quality control toolkit. It allows for in vitro endotoxin testing, which has replaced tests using animals, such as using rabbits\u2019 thermal response to judge pyrogenicity of test samples, thus leading to a less expensive and faster test of parenteral pharmaceuticals and medical devices that contact blood or cerebrospinal fluid. However, limited by the detection mechanisms of the LAL assays currently used in industry, further improvement in their performance is challenging. To address the growing demand on optimizing LAL assays for increased test sensitivity and reduced assay time, we have developed an LAL assay approach based on a detection mechanism that is different from those being used in industry, namely, gel-clot, turbidimetric, and chromogenic detection. Using a unique open-microcavity photonic-crystal biosensor to monitor the change in the refractive index due to the reaction between LAL regents and endotoxins, we have demonstrated that this approach has significantly improved the LAL assay sensitivity and reduced the assay time.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center\"><span style=\"font-size: 18pt;color: #000080\"><strong>Neuroengineering based on Photoacoustic Imaging<\/strong><\/span><\/p>\n<p>Under development.<\/p>\n<p>[su_heading size=&#8221;16&#8243; align=&#8221;center&#8221;]<span style=\"color: #800000\"><em><strong><span style=\"font-size: 18pt\">Acknowledgement to Funding Agencies<\/span><\/strong><\/em><\/span>[\/su_heading]<\/p>\n<p><span style=\"font-size: 14pt\"><strong>We are grateful for the following funding agencies for their grant support of our research projects.<\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<table class=\"aligncenter\" style=\"height: 1324px;width: 122%;border-collapse: collapse;border-color: #ffffff\" border=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 15.7102%\">\n<p style=\"text-align: center\"><span style=\"color: #000000;font-size: 14pt\"><em>National Institutes of Health\u00a0(NIH), including NCI, NIBIB, and NIGMS<\/em><\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-143 size-thumbnail\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/NIH-logo-150x150.png\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/NIH-logo-150x150.png 150w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/NIH-logo-100x100.png 100w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/td>\n<td style=\"width: 20.4198%\">\n<p style=\"text-align: center\"><em><span style=\"font-size: 14pt\">United States Department of Defense (DoD)<\/span><\/em><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-145 size-thumbnail\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/DOD-logo-150x150.jpg\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/DOD-logo-150x150.jpg 150w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/DOD-logo-300x300.jpg 300w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/DOD-logo-160x160.jpg 160w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/DOD-logo-100x100.jpg 100w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/DOD-logo.jpg 435w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 15.7102%\">\n<p style=\"text-align: center\"><span style=\"color: #000000;font-size: 14pt\"><em>National Science Foundation (NSF)<\/em><\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-146 size-thumbnail\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/NSF-logo-150x150.png\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/NSF-logo-150x150.png 150w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/NSF-logo-298x300.png 298w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/NSF-logo-160x160.png 160w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/NSF-logo-100x100.png 100w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/NSF-logo.png 477w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/td>\n<td style=\"width: 20.4198%\">\n<p style=\"text-align: center\"><span style=\"color: #000000;font-size: 14pt\"><em>Cancer Prevention Research Institute of Texas (CPRIT)<\/em><\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-144 size-thumbnail\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/Cancer-Prevention-Research-Institute-of-Texas-Logo-150x150.jpeg\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/Cancer-Prevention-Research-Institute-of-Texas-Logo-150x150.jpeg 150w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/Cancer-Prevention-Research-Institute-of-Texas-Logo-300x300.jpeg 300w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/Cancer-Prevention-Research-Institute-of-Texas-Logo-160x160.jpeg 160w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/Cancer-Prevention-Research-Institute-of-Texas-Logo-100x100.jpeg 100w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/Cancer-Prevention-Research-Institute-of-Texas-Logo.jpeg 400w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 15.7102%\">\n<p style=\"text-align: center\"><span style=\"color: #000000;font-size: 14pt\"><em>United States Department of Agriculture (USDA)<\/em><\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-150 size-full\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/USDA-logo-1-e1530920141780.png\" alt=\"\" width=\"221\" height=\"150\" \/><\/td>\n<td style=\"width: 20.4198%\">\n<p style=\"text-align: center\"><span style=\"color: #000000;font-size: 14pt\"><em>San Antonio Area Foundation\u00a0<\/em><\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-147 size-medium\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/San-Antonio-Area-Foundation-Logo-300x200.jpg\" alt=\"\" width=\"300\" height=\"200\" \/><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 15.7102%\">\n<p style=\"text-align: center\"><span style=\"color: #000000;font-size: 14pt\"><em>San Antonio Life Sciences Institute<\/em><\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-148 size-medium\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/San-Antonio-Life-Sciences-Institute-logo-300x149.jpg\" alt=\"\" width=\"300\" height=\"149\" srcset=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/San-Antonio-Life-Sciences-Institute-logo-300x149.jpg 300w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/San-Antonio-Life-Sciences-Institute-logo-768x381.jpg 768w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/San-Antonio-Life-Sciences-Institute-logo-160x79.jpg 160w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/San-Antonio-Life-Sciences-Institute-logo.jpg 871w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/td>\n<td style=\"width: 20.4198%\">\n<p style=\"text-align: center\"><span style=\"color: #000000;font-size: 14pt\"><em>UTSA-SwRi Connect Grant<\/em><\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-153 size-thumbnail\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-150x150.jpg\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-150x150.jpg 150w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-300x300.jpg 300w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-768x768.jpg 768w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-1024x1024.jpg 1024w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-160x160.jpg 160w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-100x100.jpg 100w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA.jpg 1400w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 15.7102%\">\n<p style=\"text-align: center\"><span style=\"color: #000000;font-size: 14pt\"><em>UTSA VPR Office<\/em><\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-151 size-medium\" src=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-VPR-300x138.png\" alt=\"\" width=\"300\" height=\"138\" srcset=\"https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-VPR-300x138.png 300w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-VPR-768x352.png 768w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-VPR-1024x470.png 1024w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-VPR-160x73.png 160w, https:\/\/ceid.utsa.edu\/jyye\/wp-content\/uploads\/sites\/67\/2018\/07\/UTSA-VPR.png 1278w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/td>\n<td style=\"width: 20.4198%\">\n<p style=\"text-align: center\"><span style=\"color: #000000;font-size: 14pt\"><em>Harry S Moss Heart Trust<\/em><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[su_heading size=&#8221;16&#8243; align=&#8221;left&#8221;]Research Projects[\/su_heading] Our research is focused on the development of novel biophotonics technologies technologies to tackle critical challenges in biomedical engineering and clinical translation. Laser Intravascular Lithotripsy for Coronary Artery Calcification Coronary artery calcification significantly limits the effectiveness of percutaneous coronary interventions by reducing vessel compliance, hindering device delivery, and increasing the risk &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/ceid.utsa.edu\/jyye\/research\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Research&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-13","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Research - JingYong Ye<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ceid.utsa.edu\/jyye\/research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research - JingYong Ye\" \/>\n<meta property=\"og:description\" content=\"[su_heading size=&#8221;16&#8243; align=&#8221;left&#8221;]Research Projects[\/su_heading] Our research is focused on the development of novel biophotonics technologies technologies to tackle critical challenges in biomedical engineering and clinical translation. 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